ANOTHER study finds popular e-cigarette brand causes DNA damage in lungs

Juul me once… ANOTHER study finds e-cigarettes cause DNA damage in the lungs that’s comparable to regular cigarettes

  • Researchers at McGill University, Canada exposed mice to 60 puffs a day
  • They found rodents showed signs of lung damage within a month
  • Vaping has become an epidemic among American youth amid glitzy ads

Vaping for just a month causes DNA damage comparable to smoking, another damning e-cigarette study suggests.

Researchers at McGill University in Montreal, Canada, exposed mice to the equivalent of 60 puffs of a mango-flavored Juul device daily for four weeks.

Rodents underwent cellular and molecular changes that have been linked to the formation of cancers in traditional cigarette smokers.

America is currently in the throes of a childhood vaping epidemic that has been blamed on kid-friendly flavors and glitzy storefronts.

Vaping for just one month leads to

Vaping for just one month leads to ‘widespread changes’ in the lungs and increases levels of inflammation, another study has found (file photo)

At least 2.6 million American children between the ages of 11 and 18 use e-cigarettes, according to official figures, and that number is growing.

In the latest study, scientists exposed mice to air from a Juul device, which contained nicotine.

One-third of the mice received 60 puffs of Juul per day, administered over three 20-minute sessions with a three-hour gap between each.

This was to mimic the low usage of vaping devices, the researchers said.

In a survey in November, one in ten teenagers admitted to vaping within five minutes of waking up – a sign of addiction – while a quarter said they used vapes daily.

The rest of the mice were exposed to e-liquid used in vapes, or simply to lab air.

The e-liquid – used to create the vapor – contains propylene glycol, a petroleum by-product, and vegetable glycerin, which is derived from vegetable oil.

The study focused on Juul, but studies have shown that other brands also have a detrimental effect on the lungs.

Many vape devices contain e-liquids that contain hundreds of chemicals that can be harmful to the lungs. They also contain nicotine, which can lead to vaping addiction.

After four weeks, the scientists killed the mice and examined their lungs for the effects of the Juul machines.

The results showed that mice exposed to e-cigarette vapors had higher levels of white blood cells in their lungs, indicating higher levels of inflammation.

The tests also revealed alterations in hundreds of genes in macrophages – another type of white blood cell involved in the immune response to infection or damage.

They said the alterations they observed suggested an increased risk of vaping-associated lung injury (EVALI).

Symptoms of the disease include shortness of breath, chest pain, coughing and hemoptysis – or coughing up blood. In severe cases, this can lead to death.

Since 2019, thousands of cases have been reported in the United States, with the disease strongly linked to e-cigarettes.

The researchers concluded: “Thus, e-cigarettes are not inert and can cause significant cellular and molecular changes in the lungs.

Dr Carolyn Baglole, an expert in experimental medicine at McGill University, said: “The health consequences of vaping are not known.

“Our results show that inhaling the vapor generated by a popular brand of e-cigarette causes widespread changes inside the lungs.

“Data that further underscores that these products are not inert and can lead to lung damage if used long term.”

She added: “We show that chronic low-level exposure aerosols have local immunomodulatory effects and dramatically alter protein and RNA expression at important lung sites.” has contacted Juul for comment.

Simultaneous use of e-cigs and traditional cigarettes increases the risk

– Electronic cigarettes and traditional fuel cigarettes alone can cause a host of inflammatory and heart problems

– When used simultaneously, the health effects could be even worse

– Long-term use of either has caused damage to blood vessels, although each seems to cause side effects that the other does not, suggesting that dual use of the products makes it worse the damage.

– Blood from e-cig users caused greater permeability in blood vessel cells than blood from smokers and non-tobacco users, increasing the risk of cell damage and heart disease.

– The blood of tobacco smokers had higher levels of certain circulating biomarkers of cardiovascular risk

– The study’s lead author said that using the two products together “could increase their health risks compared to using them individually”


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